Which vaccine reduces the risk of a virus-associated cancer other than HPV?

• A. HBV vaccine reduces hepatocellular carcinoma risk.
• B. Varicella vaccine reduces liver cancer risk.
• C. Influenza vaccine reduces liver cancer risk.
• D. Measles vaccine reduces liver cancer risk.

Answer: (A)

Virus-linked cancers can be prevented by vaccines that stop the infection. Hepatitis B infection is a major driver of hepatocellular carcinoma, especially when infection becomes chronic and causes ongoing liver inflammation and cirrhosis. Vaccinating against HBV blocks infection and thus lowers the chance of chronic hepatitis B developing, reducing liver cancer risk. Among the options, this vaccine uniquely targets a virus with a proven oncogenic link to liver cancer, unlike the others whose target viruses are not established cancer drivers. Therefore, the HBV vaccine best reduces a virus-associated cancer risk other than HPV.